12 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... predispose to other orthopedic ... common sites: hip ... BrighamChiefs #Bone #Joint ... #hematology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
abdominal pain, joint ... pain involving knees ... ankles and palpable rash ... clinical #photo #dermatology ... #skin #rash #physicalexam
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... Maculopapular rash ... Polyangiitis #GPA #dermatology ... #rheumatology
Gottron's Papules in Dermatomyositis

Another classic clue is Gottron's papules which are small grouped flat topped papules
extensor surfaces of joints ... (MCP, PIP, DIP, ... elbows, knees) ... Gottrons #Papules #Rash ... Dermatomyositis #Dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... interphalangeal joints ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... Extremely rare - HIV ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... vesicular eruption - Joints ... mucositis - Rash ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
of shoulder and hip ... , mucositis • Rash ... tract, and often causes ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
Psoriasis - Elbows, knees ... temples, upper lip ... honey-colored crusts ... ; pruritis #dermatology ... #rash #differential
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... Extremely rare - HIV ... diagnosis #management #hematology