1780 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Systemic disease ... SLE - Behcet Disease ... granuloma - Synovial ... Hemophilia - Synovium ... - Sickle cell disease
Synovial Fluid Analysis:

Findings (COLOR	TRANSPARENCY	VISCOSITY	WBC COUNT (PER MM3)	PMN CELL COUNT (%)	GRAM STAIN	CULTURE	PCR TEST	CRYSTALS)

By Condition (Normal 
Noninflammatory 
Inflammatory:
Synovial Fluid Analysis ... crystalline disease ... noncrystalline disease ... Infectious: Lyme disease
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Inflammatory Bowel Disease ... Arthropathy with Crohn’s Disease ... Inflammation of Synovium ... systemic autoimmune disease
Fluid Analysis 
A systematic approach to analysis of the fluid in conjunction with the clinical presentation
examinations & infectious disease ... #csf #pleural #synovial
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... accumulation in the synovial ... triggers a mild synovial ... fluid into the synovial
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Capsulitis - Synovium ... Osgood-Schlatter Disease
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... subchondral bone & synovial ... accumulation in synovial ... notable on Xray) • Synovial
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
Hydroxyapatite Deposition Disease ... Hydroxyapatite Deposition Disease ... deposition in the synovial ... Hydroxyapatite #Deposition #Disease
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Studies in Rheumatic Diseases ... and culture of synovial ... examine a drop of synovial ... connective-tissue disease ... #Rheumatic #Disease
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Hypomagnesemia Synovial ... attacks Gout: Synovial