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diagnosis differential endocrinology dermatology symptoms generalized hypothyroid pathophysiology pruritus secondary addisons adrenal alopecia constipation geriatrics hair hairloss insufficiency interpretation loss
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... Function Tests ... → Signs of ... symmetrically enlarged thyroid ... #algorithm #diagnosis
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Primary Causes ... Mellitus Liver Function ... /uremia TSH & T4 ... #causes
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism ... (low TSH, High T4 ... ) - Diagnostic Algorithm ... concern for nodular thyroid ... #Hyperthyroid #
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... #causes #diagnosis ... endocrinology #signs
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Mellitus Liver Function ... /uremia TSH & T4 ... : • Hypothyroidism ... Pruritus #secondary #systemic ... #causes
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... patients with hypothyroidism ... Pathophysiology: • T4 ... impairs musde function ... pathophysiology #signs
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
hypotension - Nausea ... - Autoimmune thyroid ... Central nervous system ... - Secondary hypothyroidism ... Insufficiency #Signs
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
• Endocrine: Hypothyroidism ... Examination: • Signs ... Scaling, pustules, crusts ... Vitamin D levels Systemic ... deficiency • Thyroid
Pathogenesis of Select Causes of Constipation in Adults and in Elderly • Mechanical (ex. Bowel Obstruction,
Pathogenesis of Select Causes ... Hypothyroidism) ... -> Thyroid hormone ... involuntary bodily functions ... enteric nervous system
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