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diagnosis differential endocrinology dermatology generalized pruritus secondary systemic amenorrhea gynecology hypothyroid hypothyroidism interpretation lowthyroid obgyn signs symptoms tfts workup
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... Function Tests ... T4 +/- T3 → Primary ... symmetrically enlarged thyroid ... #algorithm #diagnosis
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... ; in some cases, ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... #causes #diagnosis
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism ... (low TSH, High T4 ... ) - Diagnostic Algorithm ... concern for nodular thyroid ... #Hyperthyroid #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Causes == Primary ... Mellitus Liver Function ... failure/uremia TSH ... & T4: • Hypothyroidism ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Mellitus Liver Function ... failure/uremia TSH ... & T4: • Hypothyroidism ... #causes
Hypothyroidism - Differential Diagnosis Algorithm Central Hypothyroidism • Isolated TSH Deficiency • Panhypopituitarism Thyroid Hormone Resistance Iatrogenic Primary Hypothyroidism -
Differential Diagnosis Algorithm ... • Isolated TSH ... Panhypopituitarism Thyroid ... Resistance Iatrogenic Primary ... endocrinology #causes
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm No onset of menarche by age 16 with secondary
Causes of Primary ... Differential Diagnosis Algorithm ... Etiology - High FSH ... Hypothalamic: • Functional ... Hyperprolactinemia • Hypothyroidism
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