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diagnosis causes systemic dermatology endocrinology generalized hyperthyroidism pruritus secondary amenorrhea erythematosus gynecology interpretation lupus obgyn rheumatology signs sle symptoms tfts
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... Function Tests ... T4 +/- T3 → Primary ... symmetrically enlarged thyroid ... Hyperthyroidism #algorithm
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... causes #diagnosis #differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... Mellitus Liver Function ... failure/uremia TSH ... & T4: • Hypothyroidism ... #Diagnosis #Algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Diagnosis Algorithm ... Mellitus Liver Function ... failure/uremia TSH ... & T4: • Hypothyroidism
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm No onset of menarche by age 16 with secondary
Causes of Primary ... Diagnosis Algorithm ... Etiology - High FSH ... Hypothalamic: • Functional ... (e.g. eating disorder
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... (e.g. thyroid disease ... the context of primary ... pneumonitis • Diffuse ... > 1:80 • CBC, TSH
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