TFR ckd physicalexam myxoma pharmacology differential cold paraproteinemias anemia - GrepMed

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Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

• Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... disease #hemolytic #anemia

Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone

Paraproteinemias ... Autoantibodies: • WAIHA • CAD ... (-) hemolytic anemia ... due to cold IgG ... Hematology #Monoclonal #Differential

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