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rheumatology management differential syphilis signs syndrome approach behcet classification comparison degenerative disease erythematosus inflammatory joint jointdisease jointpain latent lupus myelitis
Stages of Syphilis Early Primary: • Painless chancre • Regional lymphadenopathy Early Secondary: • Fever, malaise • Rash
Stages of Syphilis ... aortic aneurysm, arteritis ... • Gummatous • Nodular ... #symptoms #signs ... #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... meningitis), MCC CNS symptoms ... is a skin prick test ... Giant retinal tears ... management #signs #symptoms
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... present both at rest ... e.g., meniscal tears ... #Joint #Pain #MSK ... #differential #diagnosis
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
The Stages of Syphilis ... - Ocular syphilis ... exposure to or symptoms ... aneurysm and coronary arteritis ... Latent #Tertiary #Diagnosis
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Headache, meningitis, ocular ... ulcerated • MSK ... infected without symptoms ... #Syphilis #stages ... #diagnosis #management
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Lots of fluid, takes ... in Rheumatoid arthritis ... joints tend to bear ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Syndrome: - Ocular ... well as inner ear ... Presentation - Systemic Symptoms ... retinopathy Lab Tests
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
peaks between the ages ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... Transverse Myelitis Diagnosis ... negative, MOG-IgG test
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Female • Peaks 3rd ... Erythematous, macular ... Differential Diagnosis ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Symptomatic: artificial tears ... Biologic: 2nd or 3rd
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