20 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: - Short ... expansion (e.g. carpal ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... overgrowth: • Carpal ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs ... /symptoms of HHS ... hypotension) DKA: Short
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... Residency @CMC_IM #Potts
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... Video by Dr. ... Meningitis #Clinical #Video ... #PhysicalExam #
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
-> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms #complications
Froment’s Test for Ulnar Nerve Palsy

This tests for pinch grip weakness caused by ulnar nerve palsy,
grip weakness caused ... Froment's Sign is ... Palsy #clinical #video ... #neurology #physicalexam ... #orthopedics #sports
Tinel's Test for Tarsal Tunnel Syndrome

Perform a Tinel's over the tarsal tunnel, attempting to reproduce pain,
numbness, or tingling caused ... Video via @open_michigan ... Syndrome #ankle #PhysicalExam ... #clinical #video ... #sports #msk #orthopedics
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
in the Spinal canal ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Kussmaul's Sign and Friedreich's Sign on Neck Examination

A middle-aged M with unknown PMH presents with dyspnea.
demonstrated in the video ... small blue-colored spot ... the underlying cause ... Friedreichs #Neck #JVP #PhysicalExam ... #Clinical #Video