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diagnosis sle erythematosus hematology activation calcium cppd deposition differential druginduced fungal infections infectiousdiseases macrophage monoclonal mycoses neurology oncology paraproteinemias pseudogout
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Cerebrovascular Disease ... #rheumatology # ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... (CNS) dysfunction ... lupus erythematosus ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... myopathy • Anti MAG ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... (NPSLE): • May ... CNS • Headache ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... the circulatory system ... Fungal #Diagnosis #Management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
joints (shoulders, wrists ... often involves the wrists ... polyarticular CPPD • Systemic ... #Rheumatology # ... diagnosis #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
disorders, including systemic ... lupus erythematosus ... and the systemic ... TAFRO #diagnosis #management ... #rheumatology #
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