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Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis: • Clinical ... : Confirmatory test ... ↑Se/Sp but very ... A/C if clinical ... #Treatment #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... HIT laboratory tests ... and to adjust treatment ... #Hematology #HIT ... #Heparin #Induced
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... +++ (Plt, Hb), Hepatic ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... Liver function tests ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... the “Chewing gum test ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... Symptoms #Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cases such as: • SLE ... tests for (not ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management