12 results
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical ... hydrocephalus, HIV ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... MNCD #Dementia #Differential
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management ... signs #symptoms #rheumatology
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
failure, esp in work-up ... /management of shock ... Troponin, TSH, CPK, HIV ... Urine Pregnancy Test ... #criticalcare
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... Gravis #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Agent Orange or Hep ... C Clinical Presentation ... Leukemia #diagnosis #workup ... #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... • Diagnostic Test ... hemolytic #anemia #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Diagnosis #Management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... Diagnosis and Workup ... glucose suppression test
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... negative, MOG-IgG test ... , Hep A/B/CMV, TB ... Myelitis #diagnosis #management ... #neurology #differential