12 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Syndrome (CAS): ... Viral Infection Clinical ... Mycoplasma, EBV, HIV ... younger pts) Differential ... • Diagnostic Test
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical ... hydrocephalus, HIV ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... MNCD #Dementia #Differential
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management ... signs #symptoms #rheumatology
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
failure, esp in work-up ... /management of shock ... Troponin, TSH, CPK, HIV ... Urine Pregnancy Test ... #criticalcare
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... Gravis #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Agent Orange or Hep ... C Clinical Presentation ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... Diagnosis and Workup ... glucose suppression test
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... salivary ducts Clinical ... phenomenon (16%) MSK ... #Rheumatology # ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... negative, MOG-IgG test ... , Hep A/B/CMV, TB ... Myelitis #diagnosis #management ... #neurology #differential