11 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
younger pts) Differential ... Symptoms: High fevers ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Agglutination - Cold agglutinins ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Chronic Diarrhea - Workup
Osmotic:
 • Consider food diary and trial avoiding certain foods or meds, Consider
Chronic Diarrhea ... - Workup Osmotic ... hydrogen breath test ... Abdominal imaging (CT, ultrasound ... #diagnosis #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Red Flags: • Fever ... deficiency Work ... Fecal occult blood test ... • Abdominal ultrasound
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... : • Acute or chronic ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... • Chronic - Think ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... adults in the west ... Lymphadenopathy • Fevers ... Leukemia #diagnosis #workup ... #oncology #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... normal/high - Chronic ... you’ll do a good workup ... Best to have an ... #Polycythemia #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Eosinophilia, asthma, chronic ... Coronary arteries - Fever ... Vasculitis: • Fevers ... retinopathy Lab Tests ... #diagnosis #rheumatology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
include low-grade fevers ... normal and can help differentiate ... universally used, ultrasound ... treatment for PMR is a chronic ... Diagnosis #Management #Rheumatology