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rheumatology management sle dermatology differential druginduced erythematosus systemic algorithm alopecia antiphospholipid apls arthritis chronic classification cll comparison dementia dil disease
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... versus DIL • Laboratory ... • Immunologic Workup ... Positive in 60-80% of cases
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... calcium-b) • Laboratory ... • Immunologic Workup ... • Immunologic Workup ... #diagnosis #management
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
1) Clinical diagnosis ... deficiency, ... laboratory ... tests + imaging ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Disease: Discoid lupus ... , Loose anagen syndrome ... texture at bald spots ... Tests: • TSH
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... and fever) and laboratory ... Differential Diagnosis ... Clinical Features ... Erythematosus #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... (to support a diagnosis ... ANA and RF (if clinical ... #workup #diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... out other causes ... other etiology • Laboratory ... blockers had the best
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Pinpoint-sized red spots ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... Treat underlying cause ... #HemeOnc #Diagnosis
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