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rheumatology approach cppd differential management pain degenerative deposition druginduced gout inflammatory jointdisease jointpain laboratory lupus pathophysiology pseudogout pyrophosphate rheumatic rheumatoid
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... crystals (gout) or calcium ... profile (e.g., calcium ... #laboratory #workup ... #diagnosis #testing
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Joint Disease ... in Rheumatoid arthritis ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... #JointPain #Diagnosis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
(shoulders, wrists ... • Underlying disease ... precipitates with calcium ... #CPPD #Gout #Comparison ... #rheumatology #
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
swelling in weird joints ... (shoulders, wrists ... culture used to diagnose ... #Rheumatology # ... diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #diagnosis #management
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