14 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
in Behcet syndrome ... Oral aphthae : SLE ... : SLE, Reactive ... #management #signs ... #symptoms #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... crystals (gout) or calcium ... profile (e.g., calcium ... #laboratory #workup ... #diagnosis #testing
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... - SLE - Behcet ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... • Immunologic Workup ... : Chronic disease ... #diagnosis #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
joints (shoulders, wrists ... often involves the wrists ... culture used to diagnose ... #Rheumatology # ... diagnosis #management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
to Joint Pain - Diagnostic ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... VASCULITIS: • Behçet ... retinopathy Lab Tests ... vasculitis, and SLE ... #rheumatology #
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... some time, let’s see ... Best to have an ... #Algorithm #workup ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... erythematosus [SLE ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology