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diagnosis blood dermatology vasculitis activation anemia classification extravascular hemolysis hemolytic intravascular macrophage mas nonpalpable palpable thromboticthrombocytopenicpurpura transfusion transfusions ttp vasculitides
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... fever • Drug reactions ... #Differential # ... Diagnosis #hematology ... #rheumatology #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #differential # ... diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... extensive skin rash ... Edema in 70% of cases ... Resolution > 15 days Differentials ... #Syndrome #dermatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... severe thrombocytopenia ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... severe thrombocytopenia ... Transfusion #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, ... leukopenia, anemia, and thrombocytopenia ... Fibrin degradation products ... #Diagnosis #Management ... #Hematology #Rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... Fibrin degradation products ... WBC count and differential ... #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... tract, and often causes ... mucositis - Rash ... disease, drug reactions ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... disease, drug reactions ... , mucositis • Rash ... tract, and often causes ... #Diagnosis #Rheumatology
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