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msk vasculitis antibodies approach autoimmune calcium gout lupus management monoarthritis monoarticular myopathy myositis oligoarthritis oligoarticular patterns polyarthritis polyarticular pseudogout pyrophosphate
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... Calcium oxalate Infectious ... infections related ... #Pain #MSK #rheumatology ... #diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... Infection • ... Viral Infections ... Joint #pain #Differential ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
Chronic CPP Crystal ... concomitant infection ... in joints and/or ... concomitant infection ... #rheumatology #
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition ... Disease (CPPD) ... Chronic CPP Crystal ... concomitant infection ... #Disease #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections ... : • Joint pain ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... to exclude are infections ... LFT • ESR • ANA ... #diagnosis #rheumatology ... #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
to exclude are infections ... ischemia • Skin: Erythematous ... Recurrent middle ear infections ... , recent viral infection ... #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... Syndrome: Fever, joint ... pain and Raynaud ... • Nonerosive arthritis ... Myositis #Myopathy #rheumatology
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