6 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(MAS) Classified ... manifestation of MAS ... erythematosus [SLE ... Plasma exchange #MAS ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Non-autoimmune ... rheumatologic diseases ... disorders (e.g. thyroid ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... and peripheral Thyroid ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... #Rheumatology #
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
mesothelioma, etc - Autoimmune ... erythematosus (SLE ... cell lymphoma Pathophysiology ... Histopathological Diagnoses ... #management #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... ALL: mediastinal mass ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Consider infectious, thyroid ... RP-ILD), dermato-rheumatologic ... (also seen in association ... Myositis #Myopathy #rheumatology