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differential hematology algorithm management vasculitis antimda5 antimda5dm classification clinical common cryofibrinogenemia dermatologic dermatomyositis disorders distribution eosinophil eosinophilia foot granulomatosis moccasin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... vasculitis (inflamed blood ... #dermatology #rash ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... vasculitis - GPA ... fever • Drug reactions ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... RA, Sjogren's, GPA ... cryoglobulins • Skin ... #dermatology #physicalexam
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... maculopapular rash ... Blood products contain ... infections with skin ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Blood products contain ... infections with skin ... #diagnosis #management ... #hematology #reactions
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... allergy, drug reaction ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... skin of inflamed ... #foot #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... tract, and often causes ... mucositis - Rash ... disease, drug reactions ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... which can plug blood ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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