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management blood dermatology differential hematology reactions stages syndrome syphilis cobalamin compared comparison deficiency dress erythemas extremity latent leg lower msk
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
- Differential Diagnosis ... Neuropathy (DM, Vit B12 ... Herpes zoster - HIV ... Immobilization) • Acute ... extremity #msk #physicalexam
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
derived from animal products ... • Common Causes ... anemia, yellow skin ... palpitations), skin ... • P/E - GI and derm
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
sweats (28%) • Skin ... rash (48%) • ... enzymes ↑ • Mild ... for 10-12 days ... #diagnosis
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... Parvovirus B19 ... observed in acute ... include: infections (HSV ... #differential #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... maculopapular rash ... Transfusion Related Acute ... infections with skin ... #Transfusions #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Edema in 70% of cases ... Skin involvement ... • SJS/TEN • Acute ... withdrawal • Mild
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... maculopapular rash ... Transfusion Related Acute ... infections with skin ... #Transfusion #diagnosis
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
Syphilis - Rash ... manifestations including acute ... similar to those of B12 ... granuIomas on skin ... Latent #Tertiary #Diagnosis
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
→ Ulcerates to produce ... weight loss • Skin ... : Rash is the most ... individuals with HIV ... Syphilis #stages #diagnosis
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