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management differential hematology arthritis cppd infectiousdiseases joint pain product reactions workup antimda5 antimda5dm approach autoimmune calcium cdi cdiff cll clostridioides
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Dermatomyositis • Fever ... onset [33-74%] • Blood ... Phenotype 1 ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... General: fever, ... nodes: 13-15%, skin ... anterior/posterior MSK
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... lasting > 30 mins - 1 ... • Rheumatic fever ... #Differential #Diagnosis ... #MSK #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... rheumatic fever ... • Chronic - Think ... #Joint #Pain #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Classification: • Acute ... with Lupus: • Chronic ... #Rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... Chronic CPP Crystal ... 12-24 Hours • Fever ... Gout #Comparison #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... maculopapular rash ... Transfusion Related Acute ... infections with skin ... #Transfusion #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Hepatomegaly • Skin ... CLL Labs: 1. ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... maculopapular rash ... Transfusion Related Acute ... infections with skin ... #Transfusions #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
on ABx) → Acute ... Diarrhea (>3 BM/d) ± blood ... mucus, Abd pain, Fever ... Perforation) Pathophysiology ... 10 mg/kg IV x 1
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