10 results
rheumatology treatment activetb dermatology disease latenttb stills syndrome tb tuberculosis activation adult adultonset algorithm ascorbicacid color ddxof differential dress hematology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
IL-6, TNF-a, ? ... : High spiking fever ... maculopapular rash ... : high fever, CRP ... #management #treatment
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... with rash - Mucocutaneous ... sulfa-drug - Skin ... #Dermatology #Rash
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... Petechial or purpuric rash ... erythematosus [SLE], AOSD ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... Rash: • Nonpruritic ... maculopapular skin ... Stills #disease #AOSD ... #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Fever >38.5 2. ... Skin involvement ... withdrawal • Mild ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... activation of macrophages ... cytokines (TNFa,lL1, IL6 ... • Clinical: fever ... #management #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... and Management ... integrity of: • Skin ... temper • Fever ... #Management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... survival is 93-95% Pathophysiology ... dysregulation: activated macrophages ... nodes: 13-15%, skin ... #Management #Signs
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Active TB: • Fever ... Tuberculosis Diagnosis ... • Tuberculin skin ... #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Active TB: • Fever ... Tuberculosis Diagnosis ... • Tuberculin skin ... #Management #Treatment
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