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rheumatology treatment 1 antimda5 antimda5dm cdiff clostridioides clostridium dermatology dermatomyositis difficile gastroenterology hemophagocytic hlh idsa infection infectiousdiseases lymphohistiocytosis nutrition scurvy
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Dermatomyositis • Fever ... onset [33-74%] • Blood ... #dermatology #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Management - GrepMed ... Diarrhea (>3 BM/d) ± blood ... mucus, Abd pain, Fever ... Perforation) Pathophysiology ... immunocompromised, IBD
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... and Management ... integrity of: • Skin ... #VitaminC #AscorbicAcid ... #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Phagocytosis of blood ... • Clinical: fever ... #management #treatment
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