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diagnosis dermatomyositis dermatology differential vasculitis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune myopathy myositis pathophysiology pm polymyositis symptoms
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... ulcerations • Skin ... Dermatomyositis #rheumatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis (DM ... processes occur in the skin ... -> Heliotrope Rash ... dehydrogenase (LD ... Pathophysiology #Signs
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... to have typical DM ... (blue-purple) rash ... Dermatomyositis #diagnosis #management ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... of shoulder and hip ... , neurologic, and ... , mucositis • Rash ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... ) • Shawl sign ... elevated < PM and DM
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