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diagnosis rheumatology hematology dermatology reactions activation antimda5 antimda5dm antinxp2 antinxp2dm capnocytophaga erythematosus fulminans fungal infections infectiousdiseases lupus macrophage mas mycoses
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Skin Rash on Physical ... Your blood cxs identify ... BIDMC Infectious Diseases ... #Rash #clinical ... #photo
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... onset [33-74%] • Blood ... severity of the disease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... (Petechial or purpuric ... rash) • Heart, ... Fibrin degradation products ... Syndrome #Diagnosis #Management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... maculopapular rash ... Blood products contain ... infections with skin ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... Blood products contain ... infections with skin ... #diagnosis #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... auricular papules Clinical ... had more severe disease ... : • ILD was diagnosed ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... arthritis, adult-onset Still ... disease, dermatomyositis ... Seizures • Strokes Skin
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Major blood ... has five major clinical ... dissemination occurs and produces ... have positive blood ... Fungal #Diagnosis #Management
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