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differential clinical dermatology rheumatology autoimmune brain causes encephalitis eschar foot hematology infections lesions meningitis moccasin monoclonal myopathy myositis oncology paraproteinemias
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Chorioretinitis • Diagnosis ... lesions + toxo IgG ... • CNS PCR 50% ... , may also see skin ... causes #radiology #neurology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea ... Over the years: rash ... Diagnosis? ... skin of inflamed ... type #clinical #photo
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... et diutinum Neurologic ... Scleromyxedema (CNS ... WAIHA • CAD • PCH ... #Differential #Diagnosis
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... : HSV 1): • Herpes ... Maculopapular rash ... • Uveitis • Rash ... Singh @rav7ks #CNS
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
of shoulder and hip ... , neurologic, and ... , mucositis • Rash ... , IgA (cmpkx deposits ... chorioretinitis, CNS
Rickettsialpox Eschar 40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis? Rickettsialpox R akari classic
Diagnosis? ... rickettsia) Dx: serology ... ; pcr from vesicle ... chickenpox, vzv, hsv ... rakari #clinical #photo
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... weakness + atrophy- Hip ... nucleotidase 1A (Anti cN ... Other Diseases: • PBC
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