10 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cause Organ Damage ... vasculitis (Henoch-Schönlein ... #diagnosis #types
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Vasculitis - Collagen disorders ... RMSF - Henoch Schonlein ... : - Autoimmune ... immunoglobulins & cryoglobulins ... • Skin biopsy
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... skin of inflamed ... #clinical #photo
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... form of delayed-type ... gyratum repens • A skin ... include: infections (HSV ... #differential #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Divided Into Two Types ... associated with autoimmune ... cryoglobulinemia Associated Disorders ... Cryofibrinogenemia Diagnosis ... • Negative causes
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... disease • Non-autoimmune ... Kikuchi disease • Type-I ... deficiencies • Autoimmune
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... Connective tissue disorders ... Cirrhosis, ETOH, autoimmune ... Comment on type ... #differential #diagnosis
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
immune-mediated, multisystem disorder ... diseases, including type ... Because the rash ... disease of the skin ... papulovesicular rash
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
LCH is a rare disorder ... Langerhans cells, a type ... inflammatory or autoimmune ... Lungs: Cysts (esp ... DIAGNOSIS • Imaging
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... weakness + atrophy- Hip ... statins - probably caused ... Other Diseases: • PBC