8 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
(GPA) Skin involvement ... Findings: • Petechiae ... Maculopapular rash ... • EGPA • Henoch-Schönlein ... #rash #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Vasculitis ... RMSF - Henoch Schonlein ... RA, Sjogren's, GPA ... cryoglobulins • Skin ... #Petechiae #Rash
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
/ Purpuric Rash ... Disseminated Gonococcal Infection ... Endocarditis, Henoch-SchönIein ... - Autoimmune Vasculitis ... #Dermatology #Skin
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... , infections, drug ... Small Vessel: Petechiae ... - Microscopic polyangiitis ... - EGPA - GPA
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... parvovirus B19 infection ... Malar rash ... • Henoch Schönlein ... Sarcoidosis • GPA
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Microscopic Polyangiitis ... present • Henoch Schonlein ... mucositis - Rash ... to exclude are infections ... • ANCA (Dx: GPA
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... reticularis & skin ... - GPA, EGPA, microscopic ... polyangiitis ... (Henoch-Schönlein
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
to exclude are infections ... , mucositis • Rash ... : Microscopic polyangiitis ... present) Henoch Schonlein ... , recent viral infection