11 results
Liver Function Tests (LFTs)
 - Aspartate aminotransferase (AST) 
 - Alanine aminotransferase (ALT) 
 - Alkaline
Liver Function Tests ... (LFTs) - Aspartate ... transpeptidase (GGT) - Bilirubin ... Indirect) - Conjugated ... Function #Tests #LFTs
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Differential Diagnosis Algorithm ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... Differential #Diagnosis #Algorithm ... #gastroenterology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... (Conjugated/DBili ... Indirect bilirubin ... (Unconjugated) ... Function #Tests #LFTs
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... Hepatocellular Pattern #LFTs ... #transaminits # ... #differential #algorithm
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Phosphatase and Bilirubin ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... bilirubin into ... Pathophysiology #Diagnosis #LFTs
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of hemolysis or liver ... an increase in conjugated ... predominantly a mixed conjugated ... • Increase in conjugated ... hepatology #diagnosis #gastroenterology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... week • Direct bilirubin ... blood cells Unconjugated ... differential #Hepatology #transaminitis ... #LFTs #RValue #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... for Transaminitis ... Burak @kwburak #LFTs ... #Algorithm #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... Diagnosis #hepatology #algorithm ... #Transaminitis ... #LFTs #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Drug #induced #Liver ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology