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hepatology diagnosis differential algorithm calling consultation hepatocellular primer referral chemistry cholestatic dili drug elevation enzymes function functiontest hepatitis idiosyncratic induced
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... Injury? ... #Enzymes #LFTs ... #Cholestatic #Transaminitis
The Gastroenterology Consult Primer Guide to Calling a GI Consult HPI: - Start with reason for consult
The Gastroenterology ... CBC - Coags, LFTs ... Focus on prior GI/Liver ... GregoryTBrennan #Liver ... #Consultation #GIConsult
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... injury) • Ischemic ... Function #Tests #LFTs ... Diagnosis #hepatology #transaminitis
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... with reason for consult ... - Vitals - LFTs ... #Consultation #GIConsult ... Referral #Hepatology #Gastroenterology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest #LFTs ... #Elevation #Transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... injury < 26 weeks ... hepatocellular injury ... differential #Hepatology #transaminitis ... #LFTs #RValue #
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