15 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Phosphorus CLL ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... syndrome • Smoldering ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute leukemia ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... (CLL) - Summary ... • Most common leukemia ... low-risk disease • Indications ... #oncology #hematology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... lymphoma & Acute leukemia ... malignancies Treatments ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
anemia DDX: Rule Out ... Chronic Myelogenous Leukemia ... Cell Leukemia ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Antithyroid medications ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... certain types of leukemia ... - Lupus - Leukemia ... Treatment: - Systemic ... #dermatology #oncology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
sex • Metabolic syndrome ... • Medications ... cortical bone Treatment ... treatment; consider ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... Renal Failure Treatment ... #oncology