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hematology differential oncology leukemia causes chronic globulin lymphocytic mds myelodysplasia myelodysplastic petechiae petechial physicalexam polycythemia protein proteingap rash syndromes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... or functional neutropenia ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Diagnosis: • ... Cytopenias: • Neutropenia ... #workup #oncology ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... deficiency Work ... cryoglobulins • Skin ... #dermatology #physicalexam
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Better call hematology ... kidneys) - Some tumors ... you’ll do a good workup ... #Algorithm #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... • Hematology: ... #differential #diagnosis ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Myeloproliferative Disease • Neutropenia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
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