5 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... Smoking, Microbial triggers ... T-cell mediated BEC injury ... Primary #Biliary #Cirrhosis ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... • NAFLD • Cirrhosis ... : • Genetic/Metabolic ... Drug-induced liver injury ... #Diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... CMV), Alcoholic cirrhosis ... NASH, Genetic / Metabolic ... #hepatology #LFTs ... transaminitis #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome #APML ... diagnosis #management #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Shock liver • Metabolic ... hepatitis: < 1 • Cirrhosis ... #hepatitis #differential ... diagnosis #algorithm #hepatology