8 results
diagnosis hematology hemophagocytic hlh lymphohistiocytosis oncology chronic differentiation fungal hemeonc infections leukemia leukostasis lymphocytic lysis mycoses sarcoidosis symptoms tafro thrombocytopenia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... the study) • Triggers ... ATRA treatment Pathophysiology ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... workup #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... • Triggers: Diuretics ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... with the HLH syndrome ... Presentation • Common Signs ... Pathophysiology ... #Hematology #HemeOnc
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... and increased B-cell ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... Low or absent NK cell ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... Aspergillosis Pathophysiology ... becomes a yeast cell ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
Angioimmunoblastic T cell ... Intravascular large B cell ... lymphoma Pathophysiology ... TAFRO #diagnosis #management ... #rheumatology #
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