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diagnosis hematology behcet cerebritis differentiation disease erythematosus fungal hemeonc hemophagocytic hlh infections leukostasis lupus lymphohistiocytosis lysis mycoses neurology oncology sle
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... the study) • Triggers ... ATRA treatment Pathophysiology ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... • Triggers: Diuretics ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #neurology #rheumatology ... cerebritis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Presentation • Common Signs ... Pathophysiology ... #Hematology #HemeOnc
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO TAFRO syndrome ... cell lymphoma Pathophysiology ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
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