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diagnosis hematology neurology syndrome oncology acromegaly aflp als amyotrophic apml classification clinical differentiation encephalopathy endocrinology fatty hodgkins lateral leukostasis liposclerosing
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... infiltration) Differential ... Liver #Pregnancy #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... Enhancement - TM and tumor ... Myelitis #diagnosis #management ... #neurology #differential
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... pancreatic islet cell tumor ... Differential Diagnosis ... • Pituitary MRI ... or refractory cases
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Classification: • The tumor ... predominant HL - The tumor ... Immunohistochemical studies (to differentiate ... #oncology #management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... MRI: Brain, cervical ... conditions listed in differential ... neurology #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... the underlying cause ... Syndrome #diagnosis #management
Liposclerosing Myxofibrous Tumor (LSMFT) - MSK Radiology Imaging Findings: • Geographic lucent lesion with sclerotic margin in
Liposclerosing Myxofibrous Tumor ... Case description ... preferable with MRI ... If change or symptoms ... Differential diagnosis
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