17 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Crises can be precipitated ... The underlying pathophysiology ... Can be triggered ... #Features #Signs ... #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Guidelines for Crises ... Treatment depends ... (late sign) (→ ... Phaeochromocytoma Neurologic ... Guidelines for crises
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
prostaglandin E2 • Triggered ... Body temperature rises ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... - Erosions and crusts
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Guidelines for Crises ... of more of the signs ... re-administration of possible trigger ... Guidelines for crises ... Checklist #Diagnosis #Management
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... life • M=F Symptoms ... and Signs: 50% ... Less common symptoms ... and signs: •
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
muscles: “myasthenic crises ... - Peek sign ... Myasthenia Crises ... Gravis #diagnosis #management ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... Neurological symptoms ... Syndrome #diagnosis #management ... #neurology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Diagnosis and Management ... ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... CNS inflammatory cause ... #Treatment #Neurology