23 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... Crises can be precipitated ... The underlying pathophysiology ... Can be triggered ... Features #Signs #Symptoms
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Guidelines for Crises ... Malignant hyperthermia crisis ... Phaeochromocytoma Neurologic ... Guidelines for crises ... Checklist #Diagnosis #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... • Triggers: Diuretics ... : • Pathophysiology ... TLS #diagnosis #management
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
prostaglandin E2 • Triggered ... Body temperature rises ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Dizziness and Vertigo Algorithm
Presyncope:
 • Feels "faint" or like they are going to "pass out"
 •
"pass out" • Symptoms ... may be triggered ... Associated with nausea ... differential #diagnosis #neurology ... #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... Neurological symptoms ... #diagnosis #management ... #neurology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... : (distinct symptoms ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... Pathophysiology ... tendency to fall • Triggers ... #treatment #neurology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... Clinical Signs/Symptoms ... - Erosions and crusts ... erosions in ~20% Management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... muscles: “myasthenic crises ... Myasthenia Crises ... Gravis #diagnosis #management ... #neurology