9 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
cells can go on to block ... The underlying pathophysiology ... Can be triggered ... #Features #Signs ... #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... into serum • Triggers ... with tetany or cardiac ... TLS #diagnosis #management
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is unconscious, signs ... is conscious, symptoms ... Intraoperative #Checklist ... #Diagnosis #Management
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
in Anaesthesia Signs ... bradycardia, conduction blocks ... problem. ❸ Call for cardiac ... Intraoperative #Checklist ... #Diagnosis #Management
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia
• Can occur with deliberate or accidental
Central Neuraxial Block ... Guidelines for Crises ... that may mimic signs ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
Guidelines for Crises ... Signs: hypotension ... decreased ETCO2 Symptoms ... unexplained loss of cardiac ... Intraoperative #Checklist
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Guidelines for Crises ... of more of the signs ... re-administration of possible trigger ... Intraoperative #Checklist ... #Diagnosis #Management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
MANIFESTATIONS: • The cardinal ... than one after symptom ... the underlying pathophysiology ... Syndrome #diagnosis #management ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... Myelitis #diagnosis #management ... #neurology #differential