21 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Alkalosis - Differential ... , Gitelman Syndrome ... Diagnosis #Algorithm #Nephrology ... #Causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Alkalosis - Differential ... , Gitelman Syndrome ... Adenoma, BAH, AME ... #Primary #Metabolic
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... → Hypokalemia Metabolic ... alkalosis - ... #Syndrome #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... the indicated causes ... #Metabolic #Alkalosis
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... ingestion, Congenital AME ... furosemide-like lesion) • Gitelman ... #Diagnosis #Causes ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal ... Hypochloremic metabolic ... Rhabdomyolysis Treatment ... #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
alkalosis - Fistulas ... - Bartter - Gitelman ... metabolic alkalosis ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... Pressure: - Metabolic ... Alkalosis: Emesis ... , Gitelman syndrome
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
alkalosis ↓ ↑ ... alkalosis/Resp ... D-lactate (short bowel syndrome ... of Metabolic Alkalosis ... Diagnosis #Summary #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Alkalosis - Differential ... , Gitelman Syndrome ... Diagnosis #Algorithm #Nephrology ... #Causes