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rheumatology cppd management bandemia calcium cbc degenerative deposition differential gout inflammatory jointdisease jointpain neutrophil pseudogout pyrophosphate sjogrens syndrome versus wbc
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
shoulders, wrists, elbows ... • Underlying disease ... states Pathophysiology ... if < 50 Years Age ... #CPPD #Gout #Comparison
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
mechanical forces that are ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... #JointPain #Diagnosis ... #pathophysiology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Band neutrophils are ... Differential Diagnosis ... • Autoimmune diseases ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Decades (can be any age ... Sjogren's Syndrome Diagnosis ... /aggregate) of CD4 ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... shoulders, wrists, elbows ... if < 50 years age ... #Rheumatology # ... diagnosis #management
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