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hematology leukemia cll lymphocytic management aplastic differential hemeonc mastoiditis mds monoclonal myelodysplasia myelodysplastic paraproteinemias pathophysiology signs syndromes workup
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Constitutional Syndromes ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
findings Acute or Chronic ... 3: Necrosis of bone ... vomiting, dizziness, vertigo ... pathophysiology #signs #symptoms ... #diagnosis #otology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... - Progressive bore ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... age 70 years Symptoms ... Failure • Chronic ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... • Neutropenia, anemia ... Warm AIHA • Bone ... #workup #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Splenic Marginal Zone ... et diutinum Neurologic ... (-) hemolytic anemia ... #Differential #Diagnosis ... #Oncology
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