11 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... numbness, decreased reflexes ... Pathophysiology ... of bacilli to bone ... in ALL patients
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... horizontal movements; also ... Motor/Sensory: • Tone ... • Examine for signs ... #PhysicalExam #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
tumour, stone, BPH ... causing Decreased tone ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Transplantation including bone ... Etiology: • Pathophysiology ... Neurological symptoms ... edema visualized as
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
in transitional zone ... hormones, urine reflux ... bladder stones #BPH ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
surgery, trauma, and bone-marrow ... depressed deep tendon reflexes ... after symptom onset ... the underlying pathophysiology ... diagnosis #management #neurology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Functional: Low BP ... / Hypovolemia NEUROLOGIC ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
and Signs: 50% ... and signs: • ... hypotension (may reflect ... leukocytosis, psychiatric ... certain drugs (such as