14 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... numbness, decreased reflexes ... Pathophysiology ... of bacilli to bone ... in ALL patients
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... horizontal movements; also ... Motor/Sensory: • Tone ... • Examine for signs ... #PhysicalExam #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology ... #diagnosis #management
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... Mucous membranes • Bone ... • Persons with psychiatric ... and tachypnea As ... Psychiatric symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Transplantation including bone ... Etiology: • Pathophysiology ... Neurological symptoms ... Syndrome #diagnosis #management ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
surgery, trauma, and bone-marrow ... depressed deep tendon reflexes ... after symptom onset ... the underlying pathophysiology ... #neurology
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
and Signs: 50% ... and signs: • ... hypotension (may reflect ... leukocytosis, psychiatric ... certain drugs (such as
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
in transitional zone ... hormones, urine reflux ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs ... #Symptoms #Diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... pain that worsens as ... GCA #Temporal #Signs ... #Management