39 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Alcohol, Medication ... obstruction, HELLP Syndrome ... #Diagnosis #Causes
Right Upper Quadrant Pain
Liver:
 - Infectious: Acute viral hepatitis, Liver abscess
 - Non-infectious: hepatitis (Alcohol, Medications),
Quadrant Pain Liver ... viral hepatitis ... (Alcohol, Medications ... ), Budd-Chiari syndrome ... #differential #diagnosis
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
liver failure ... Subclinical myocardial injury ... lung injury, ... Bone marrow ... Signs #Symptoms #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... vein: Budd-chiari syndrome ... hemolysis) • ALP: Bone ... #injury #hepatitis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Abdominal Compartment Syndrome ... #Kidney #Injury ... #nephrology #causes
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... Viral Hepatitis ... gastroenterology #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... duration), Several medications ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Injury #Diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... ) • Liver failure ... tract infection • Medications ... Classification #diagnosis ... #nephrology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... hemolysis) • ALP: Bone ... • Gilbert's syndrome ... #chemistry #diagnosis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... injury (INR > 2 ... > 3 mg/dL) or acute ... liver failure