19 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework ... sustained over a one-hour ... shoulder pain, collateral ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... the blood and bone ... blood smear • Bone ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Aplastic Anemia Clinical ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
One and a Half Syndrome ... gaze palsy to one ... result is that one ... the hospital, diagnosed ... #OneAndAHalf #One
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Warm AIHA • Bone ... • Richter’s Syndrome ... lymphoma • Marginal zone ... #workup #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Splenic Marginal Zone ... capillary leak syndrome ... TMA • Marginal zone ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... Transplantation including bone ... Reversible course Differential ... mean 58 mg/dL in one
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... think about three clinical ... retraction of one ... contralateral one ... Ptosis #neurology #Differential
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Diagnosis Framework ... Normal: Air > bone ... hearing loss: Bone ... II ○ Susac’s syndrome ... #Diagnosis #otology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... necrosis HELLP Syndrome ... Microvesicular fat in zone ... hepatitis #comparison #differential ... #diagnosis #icp