9 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... predispose to other orthopedic ... #hematology
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
in case of Pneumonia ... Differential Bilat ... interstitial lung disease ... #BLines #Bilateral ... #clinical #ultrasound
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • softening of bones ... of feet, thigh bones ... Malnutrition • Wilson's disease ... Phosphatase: • Other causes
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... multifactorial mechanisms Hematologic ... Classification #Diagnosis #Differential ... #Causes
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammation of the bones ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... osteoarticular and skin disease
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... ) - Bone Marrow ... : • Clinical ( ... NTM #Infections #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Shock, Autoimmune disease ... Transplantation including bone ... Reversible course Differential ... the underlying cause ... with AEDs until cause
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... number of sites of disease ... classification #hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
loss of muscle, bone ... the Journal of Clinical ... reasoning during clinical ... Anemia of renal disease ... pathophysiology #differential