22 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... • XR, MRI to ... #differential #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Pathogenesis and clinical ... damage weakens the bone ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... • MRI is more sensitive ... tuberosity Differential diagnosis ... #mri #clinical ... #Radiology #diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... Clinical Signs ... decreased reflexes Pathophysiology ... of bacilli to bone ... : - MRI is modality
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... , Biological + Bone ... Assessment • Clinical ... /ml, ↑ LDH • Bone
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... out other causes ... - MRI: inflammation ... osteoarticular and skin disease
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... super-antigen mediated disease ... Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... MCTD - Bechet disease
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pathogenesis and clinical ... phosphorous in bones ... Pseudogout #CPPD #Disease ... Signs #Symptoms #Pathophysiology ... #Diagnosis
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
Bilateral B-Lines in case ... Progressive URI ... interstitial lung disease ... NOT definitively diagnose ... #Lung #POCUS #clinical