117 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Most common symptoms ... - Bone symptoms ... Diagnosis #Algorithm #hepatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... Pain #SickleCell #Disease ... diagnosis #causes #hematology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... StressFractures #msk #orthopedics ... pathophysiology #symptoms
Dupuytren's Contracture (Palmar Fibromatosis) on Physical Exam

#Dupuytrens #Contracture #Palmar #Fibromatosis #clinical #video #physicalexam #msk #hand #orthopedics
#Fibromatosis #clinical ... #video #physicalexam ... #msk #hand #orthopedics ... #rheumatology
Raynaud's Phenomenon on Physical Exam

#Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
Raynauds #Syndrome #disease ... #phenomenon #clinical ... #video #physicalexam ... fingers #hands #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... - B symptoms ... Noncontiguous spread • Clinical ... Lymphomas • Other hematologic ... #differential #hematology
Clinical Disease Characteristics and Suggested Algorithm for Diagnostic Evaluation of Patients With Symptoms of Polymyalgia Rheumatica

#Diagnosis
Clinical Disease ... Patients With Symptoms ... #Diagnosis #Rheumatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Neuropathy ALP is critical ... Malnutrition • Wilson's disease ... mineralization Symptoms ... Hyophosphatasia #hepatology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... in GBA1 gene Clinical ... Osteonecrosis, bone ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
/or suspicious clinical ... symptoms/signs ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... Abnormal #Algorithm #Hepatology